Usnic acid Alias: lichen acid
Plant sources : the Song Luoke (Usneaceae) plant Usnea Usnea diffracta Vain. , And long Usnea Usnea longissima Ach. Dried lichens .
Nature: yellow rhombic prismatic crystals ( acetone ) . Melting point 204 ℃. Polarimetry 509.4 ° (c = 0.697, chloroform ) . 25 ℃ the solubility (g/100ml water ) < 0.01 , acetone 0.77 , ethyl acetate 0.88 , ethanol 0.02 , 7.32 furfural , sugar alcohols 1.21 . Chemical synthesis or biological synthesis.
This product is a broad-spectrum antibiotic , for most Gram-positive bacteria have a strong inhibitory effect , can also inhibit the growth of Mycobacterium tuberculosis . If combined with a small amount of streptomycin , the inhibitory effect of TB can be greatly enhanced, low toxicity . Usnea acid on parasite, Trichomonas vaginalis also inhibited. For partial hepatectomy in rats fed Usnic acid promote liver regeneration. Formulations containing this product to cancer patients have significant therapeutic effect. Clinically, there is a certain effect on malaria . For trauma, burns and skin diseases, inflammation of the cervix , cracked nipples , prevent perineal rupture have a certain effect . In addition , antibiotics can be used as ” feeding pyrazole ,” the material .