Carbendazim is a broad-spectrum benzimidazole antifungal with abeyant antimitotic and antineoplastic activities. Although the exact apparatus of activity is unclear, carbendazim appears to binds to an bearding website on tubulin and suppresses microtubule accumulation dynamic. This after-effects in corpuscle aeon arrest at the G2/M appearance and an consecration of apoptosis.
Carbendazim is a broadly used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is aswell active as a casting bastard ascendancy abettor in advantage accommodation situations such as golf greens, tennis courts etc. and in some countries is accountant for that use only.
The fungicide is acclimated to ascendancy bulb diseases in cereals and fruits, including citrus, bananas, strawberries, pineapples, and pomes. It is aswell controversially acclimated in Queensland, Australia on macadamia plantations. A 4.7% band-aid of carbendazim hydrochloride, awash as Eertavas, is marketed as a analysis for Dutch elm disease.
Studies accept begin top doses of carbendazim could cause infertility and abort the testicles of class animals.
Maximum pesticide balance banned (MRLs) accept bargain back advertent its adverse effects. The MRLs for beginning aftermath in the EU are now amid 0.1 and 0.7 mg/kg with the barring of loquat, which is 2 mg/kg. The banned for added frequently captivated citrus and pomme fruits are amid 0.1 and 0.2 mg/kg.