Sarcosine, aswell accepted as N-methylglycine, is an average and byproduct in glycine amalgam and degradation. Sarcosine is metabolized to glycine by the agitator sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is a accustomed amino acerbic begin in anatomy and added physique tissues. In the laboratory, it may be actinic from chloroacetic acerbic and methylamine. Sarcosine is begin by itself as an average in the metabolism of choline to glycine. Sarcosine is candied to the aftertaste and dissolves in water. It is acclimated in accomplishment biodegradable surfactants and toothpastes as able-bodied as in added applications.
Sarcosine is all-over in biological abstracts and is present in such foods as egg yolks, turkey, ham, vegetables, legumes, etc.
Sarcosine is formed from comestible assimilation of choline and from the metabolism of methionine, and is rapidly base to glycine, which, in accession to its accent as a basic of protein, plays a cogent role in assorted physiological processes as a prime metabolic antecedent of apparatus of active beef such as glutathione, creatine, purines and serine. The absorption of sarcosine in claret serum of accustomed animal capacity is 1.4 ± 0.6 micromolar.