Drospirenone Description

Drospirenone is a constructed progestin that is an analog to spironolactone. It is begin in a amount of bearing ascendancy formulations. Drospirenone differs from added constructed progestins in that its pharmacological contour in preclinical studies shows it to be afterpiece to the accustomed progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated action of the renin-angiotensin-aldosterone system, and is not androgenic. It was apparent in beastly studies that drospirenone exhibits antiandrogenic action anticipation from accent sex gland advance in castrated, androgen-treated, adolescent rats.

Drospirenone differs from added constructed progestins in that its pharmacological contour in preclinical studies shows it to be afterpiece to the accustomed progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated action of the renin-angiotensin-aldosterone system, and is not androgenic.

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