Calcitonin, chicken is a beeline peptide hormone absolute 32 amino acids, is bogus by the thyroid parafollicular beef (parafollicular cells, aswell accepted as C-cells) in the animal body. Fish, reptiles, birds, mammals, who accept begin that the hormone. The capital action is to abate hypercalcemia. Calcitonin usually not actual cogent accent for the adjustment of animal claret calcium (Ca2) constant. Is buried by the thyroid C cells. In added words, the thyroid C beef bury calcitonin endocrine cells. Corpuscle physique were round, oval, or irregular-shaped, individual anchored thyroid follicular wall, abutting to the basement membrane, or flocks broadcast interfollicular organization, aswell accepted as the parafollicular cells. Calcitonin is a hormone accepted to participate in calcium and phosphorus metabolism. Calcitonin contains a individual disulfide bond, which causes the amino abuttals to accept the appearance of a ring. Alternative splicing of the calcitonin pre-mRNA can crop a mRNA encoding calcitonin gene-related peptide; that peptide appears to action in the afraid and vascular systems. The calcitonin receptor has been cloned and apparent to be a affiliate of the seven-transmembrane, G protein-coupled receptor family.
Calcitonin, chicken parafollicular beef originated in medullary thyroid blight diagnosis, to actuate the acceptation of surgical analysis and ascertainment recurrence. Malignancies, such as oat corpuscle carcinoma, lung cancer, pancreatic cancer, uterine cancer, prostate blight and the like. Some ectopic endocrine syndrome, astringent cartilage disease, branch disease, and pheochromocytoma. Thyroid surgically removed, and astringent hyperthyroidism. This artefact is acclimated to amusement abstinent to astringent affection of osteitis deformans. Paget’s ache patients with affection of cartilage affliction and cartilage deformities, affection abortion and deafness should accede application this treatment. A lot of patients with Paget osteitis alone a baby allocation of cartilage captivation asymptomatic; balmy affection can be acclimated anti-inflammatory painkillers to ease. Application this artefact for patients with asymptomatic Paget prophylaxis is no affirmation to prove beneficial. Abstinent to astringent Paget ache afterwards application this product, a lot of patients are about in the analysis of 2 to 8 weeks, serum acrid phosphatase and urinary hydroxy proline absorption decreased affliction affection improved. Calcitonin abiding analysis of 6 to 9 months afterwards the ameliorative aftereffect and gradually access (performance advance of analytic and biochemical parameters), and assuredly accomplished a plateau.
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